Gleevec Cancer Drug Reported To Work In Alzheimer’s disease also working in Niemann Pick Type C mouse

A New York Times story is reporting that Paul Greengard (and his dog Alpha), who won a Nobel Prize for his work on signaling in brain cells, has found that the cancer drug Gleevec, is a new potential drug target for Alzheimer’s disease and blocks gamma secretase activating protein. Rudolph Tanzi and Paul Aisen are […]

Good Morning America Features Addi and Cassi’s Fight Against Fatal Brain Disease

On May 1st, 2008, Addi and Cassi’s fight against Niemann Pick Type C was featured on ABC News Good Morning America. Please spend a few minutes to read the entire story and watch the 4 minute segment.  We are very grateful to Good Morning America for taking the time to create this thoughtful and caring […]

Re-Thinking Drug Development Roadmap In United States

No Insurance. No Money. No Drugs. No Hope. We Need A New RoadMap For The Future Of 7,000+ diseases that affect humankind, treatments for only 200 of these diseases are being actively pursued by pharmaceutical and biotechnology companies. With the cost of bringing a new drug to market now exceeding $1 billion dollars and taking […]

Hope, Faith and Love – Our Nations Robotic Heros!

We have returned from the National Chemical Genomics Center (NCGC) and are busy working on pushing forward new therapy ideas for Addi and Cassi and Niemann Pick Type C disease using state-of-the-art cheminformatics methods. The robotic equipment the NCGC has established for testing cells and profiling compounds for large collections of chemicals is incredible.  The […]

The National Chemical Genomics Center, Rockville, Maryland

We are leaving tomorrow, Nov. 26, 2008, for a special meeting to discuss accelerating research into Niemann Pick Type C disease at the National Chemical Genomics Center (NCGC) located in Rockville, Maryland. The National Institutes of Health (NIH) established the NCGC to create a national resource for the study of protein and cell functions so they can […]