Crossing The Blood Brain Barrier – Does Cyclodextrin Make Its Way Into The Brain?
May 2, 2009 by Daddy
Filed under Cyclodextrin
Dr. David Begley, one of the world’s leading blood brain barrier experts at Kings College London is working on a research project we are currently funding on cyclodextrin and the blood brain barrier. We want to answer the following question. Does hydroxy propel beta cyclodextrin (HPBCD) cross the blood brain barrier? Since less than 5% […]
Cystic Fibrosis and Niemann Pick Type C Linked Through Cholesterol Abnormalities and cAMP Cell Signaling Pathway
April 26, 2009 by Chris Hempel
Filed under Cystic Fibrosis, Related Diseases
A few months ago, I wrote a blog about the connection points between Duchenne Muscular Dystrophy (DMD) and Niemann Pick Type C (NPC) and how more research dollars are needed for collaborative research projects between the two deadly diseases. Today, I am writing about the connections between Cystic Fibrosis (CF) and Niemann Pick Type C. […]
Mom Finds Experimental Drug for Twins’ Fatal Cholesterol Condition; FDA Approves Treatment Under Compassionate Use Program
April 20, 2009 by Chris Hempel
Filed under Videos
Good Morning America reports on the Food and Drug Administration’s approval of Addi and Cassi’s compassionate use Investigational New Drug Application to give them intravenous infusions of cyclodextrin, a non toxic sugar compound found in everyday food products. Cyclodextrin may have the ability to remove trapped cellular cholesterol from Addi and Cassi’s brain, liver and […]
Cyclodextrin As A Therapeutic “Drug” For HIV AIDS, Niemann Pick Type C and other Viruses
Addi and Cassi’s first round of cyclodextrin infusions have been going smoothly at Renown Regional Medical Center in Reno, Nevada. We’re now into our third day of continuous infusions of hydroxy propel beta cyclodextrin (HPBCD) into the girls’ bloodstreams and they don’t seem to be experiencing any negative side effects. I feel as if it’s […]
KTVU Reports On New Treatment for HIV/AIDS and Deadly Childhood Cholesterol Disease
San Francisco Bay Area Television station KTVU Channel 2 tells the story about how HIV/AIDS and rare childhood cholesterol disease are connected and how a promising new treatment with a sugar compound called cyclodextrin could help both deadly diseases. Our thanks to KTVU for airing this 4 minute segment. (April 1st, 2009)
