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	<title>The Addi and Cassi Fund - Niemann Pick Type C &#187; intrathecal cyclodextrin</title>
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	<description>Treatments &#38; Cures for Niemann Pick Type C - Childhood Alzheimer&#039;s</description>
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		<title>National Institues of Health Announces Cyclodextrin Clincial Trial For Fatal Cholesterol Disease Called Niemann Pick Type C</title>
		<link>http://addiandcassi.com/nih-announces-cyclodextrin-trial-niemann-pick-type/</link>
		<comments>http://addiandcassi.com/nih-announces-cyclodextrin-trial-niemann-pick-type/#comments</comments>
		<pubDate>Tue, 16 Aug 2011 21:48:22 +0000</pubDate>
		<dc:creator>Chris Hempel</dc:creator>
				<category><![CDATA[Featured Stories]]></category>
		<category><![CDATA[2-Hydroxypropyl-beta-Cyclodextrin]]></category>
		<category><![CDATA[Cholesterol]]></category>
		<category><![CDATA[Cyclodextrin]]></category>
		<category><![CDATA[Dr. Caroline Hastings]]></category>
		<category><![CDATA[Dr. Forbes “Denny” Porter]]></category>
		<category><![CDATA[FDA]]></category>
		<category><![CDATA[HPBCD]]></category>
		<category><![CDATA[intracerebroventricular cyclodextrin]]></category>
		<category><![CDATA[intrathecal cyclodextrin]]></category>
		<category><![CDATA[intravenous cyclodextrin]]></category>
		<category><![CDATA[Medtronic SynchroMed pump]]></category>
		<category><![CDATA[National Center for Advancing Translational Sciences]]></category>
		<category><![CDATA[Niemann Pick Type C]]></category>
		<category><![CDATA[Niemann Pick TYpe C cats]]></category>
		<category><![CDATA[NIH Bench-to-Bedside Grant]]></category>
		<category><![CDATA[NIH cyclodextrin clinical trial]]></category>
		<category><![CDATA[NIHs Therapeutics for Rare and Neglected Diseases]]></category>
		<category><![CDATA[TRND]]></category>

		<guid isPermaLink="false">http://addiandcassi.com/?p=3369</guid>
		<description><![CDATA[Over the past three years, many Niemann Pick Type C families as well as physicians treating NPC patients worldwide have contacted Dr. Caroline Hastings and I regarding Addi and Cassi&#8217;s treatments with hydroxypropyl-beta-cyclodextrin. Since sharing our intravenous (IV) and intrathecal (IT) cyclodextrin treatment protocols with NPC families and doctors in the U.S. and other countries, [...]]]></description>
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		<slash:comments>6</slash:comments>
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		<title>Gleevec Cancer Drug Reported To Work In Alzheimer&#8217;s disease also working in Niemann Pick Type C mouse</title>
		<link>http://addiandcassi.com/gleevec-cancer-drug-reported-work-alzheimers-disease-working-niemann-pick-type-mouse/</link>
		<comments>http://addiandcassi.com/gleevec-cancer-drug-reported-work-alzheimers-disease-working-niemann-pick-type-mouse/#comments</comments>
		<pubDate>Thu, 02 Sep 2010 14:28:57 +0000</pubDate>
		<dc:creator>Chris Hempel</dc:creator>
				<category><![CDATA[Featured Stories]]></category>
		<category><![CDATA[Alzheimers]]></category>
		<category><![CDATA[Amyloid beta]]></category>
		<category><![CDATA[Brian Druker]]></category>
		<category><![CDATA[Childhood Alzheimers]]></category>
		<category><![CDATA[Dr. Christopher Austin]]></category>
		<category><![CDATA[gamma secretase]]></category>
		<category><![CDATA[gamma secretase activating protein]]></category>
		<category><![CDATA[Gleevec]]></category>
		<category><![CDATA[Imatinib]]></category>
		<category><![CDATA[intrathecal cyclodextrin]]></category>
		<category><![CDATA[intrathecal gleevec]]></category>
		<category><![CDATA[Kaj Blennow]]></category>
		<category><![CDATA[Katarina Kågedal]]></category>
		<category><![CDATA[National Chemical Genomics Center]]></category>
		<category><![CDATA[Niemann Pick Type C]]></category>
		<category><![CDATA[Nilotinib]]></category>
		<category><![CDATA[Nobel Prize]]></category>
		<category><![CDATA[Novartis]]></category>
		<category><![CDATA[Paul Aisen]]></category>
		<category><![CDATA[Paul Greengard]]></category>
		<category><![CDATA[Pontifica Universidad Catolica de Chile]]></category>
		<category><![CDATA[Rudolph Tanzi]]></category>
		<category><![CDATA[tyrosine kinase inhibitor]]></category>

		<guid isPermaLink="false">http://addiandcassi.com/?p=3052</guid>
		<description><![CDATA[A New York Times story is reporting that Paul Greengard (and his dog Alpha), who won a Nobel Prize for his work on signaling in brain cells, has found that the cancer drug Gleevec, is a new potential drug target for Alzheimer’s disease and blocks gamma secretase activating protein. Rudolph Tanzi and Paul Aisen are [...]]]></description>
		<wfw:commentRss>http://addiandcassi.com/gleevec-cancer-drug-reported-work-alzheimers-disease-working-niemann-pick-type-mouse/feed/</wfw:commentRss>
		<slash:comments>3</slash:comments>
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		<title>IND Application Filed With FDA To Bring Cyclodextrin Into The Brain To Treat Fatal Childhood Cholesterol Disease</title>
		<link>http://addiandcassi.com/ind-filings-intratehcal-cyclodextrin-treatment-fda/</link>
		<comments>http://addiandcassi.com/ind-filings-intratehcal-cyclodextrin-treatment-fda/#comments</comments>
		<pubDate>Sat, 17 Jul 2010 17:03:08 +0000</pubDate>
		<dc:creator>Chris Hempel</dc:creator>
				<category><![CDATA[Cyclodextrin]]></category>
		<category><![CDATA[Childhood Alzheimers]]></category>
		<category><![CDATA[Children's Hospital & Research Center Oakland]]></category>
		<category><![CDATA[CYCLO]]></category>
		<category><![CDATA[dementia treatment]]></category>
		<category><![CDATA[Dr. John Dietschy]]></category>
		<category><![CDATA[FDA]]></category>
		<category><![CDATA[Hydroxy Propel Beta Cyclodextrin]]></category>
		<category><![CDATA[intrathecal cyclodextrin]]></category>
		<category><![CDATA[Investigational New Drug Application]]></category>
		<category><![CDATA[New Cholesterol Drug]]></category>
		<category><![CDATA[Niemann Pick Type C]]></category>
		<category><![CDATA[NINDS]]></category>
		<category><![CDATA[rare disease]]></category>
		<category><![CDATA[UT Southwestern]]></category>

		<guid isPermaLink="false">http://addiandcassi.com/?p=2873</guid>
		<description><![CDATA[After months and months of work and input by doctors and researchers, Dr. Caroline Hastings at Children&#8217;s Hospital Research Center Oakland filed our second Investigational New Drug application (IND) with the FDA on July 14, 2010. The 200+ page IND filing details our request to deliver hydroxy-propel-beta-cyclodextrin (HPBCD or CYCLO) directly into Addi and Cassi&#8217;s [...]]]></description>
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		<slash:comments>4</slash:comments>
		</item>
		<item>
		<title>Family of Twins with Rare and Fatal Cholesterol Disease To Seek FDA Approval To Deliver Cyclodextrin Into the Brain</title>
		<link>http://addiandcassi.com/family-of-twins-with-rare-and-fatal-cholesterol-disease-to-seek-fda-approval-to-deliver-cyclodextrin-into-the-brain/</link>
		<comments>http://addiandcassi.com/family-of-twins-with-rare-and-fatal-cholesterol-disease-to-seek-fda-approval-to-deliver-cyclodextrin-into-the-brain/#comments</comments>
		<pubDate>Fri, 15 Jan 2010 21:11:37 +0000</pubDate>
		<dc:creator>Chris Hempel</dc:creator>
				<category><![CDATA[Cyclodextrin]]></category>
		<category><![CDATA[Cyclodextrin News]]></category>
		<category><![CDATA[Begley Kings College London]]></category>
		<category><![CDATA[Children's Hospital Oakland]]></category>
		<category><![CDATA[Cholesterol]]></category>
		<category><![CDATA[Compassionate Use IND Cyclodextrin]]></category>
		<category><![CDATA[Extraordinary Measures]]></category>
		<category><![CDATA[FDA]]></category>
		<category><![CDATA[identical twins]]></category>
		<category><![CDATA[intrathecal cyclodextrin]]></category>
		<category><![CDATA[intraventricular drug delivery]]></category>
		<category><![CDATA[John Crowley]]></category>
		<category><![CDATA[Lysosomal Disease Network World Conference 2010]]></category>
		<category><![CDATA[Niemann Pick Type C]]></category>
		<category><![CDATA[pharmacokinetics  cyclodextrin]]></category>
		<category><![CDATA[rare disease]]></category>
		<category><![CDATA[xanthomas]]></category>

		<guid isPermaLink="false">http://addiandcassi.com/?p=2422</guid>
		<description><![CDATA[The tagline of the new movie, Extraordinary Measures, about John Crowley’s fight to save his children from the rare and fatal Pompe disease is&#8230;.Don’t Hope For a Miracle – Make One! We are now working on making our own miracle  &#8211; a new compassionate use investigational new drug (IND) protocol and application that we plan [...]]]></description>
		<wfw:commentRss>http://addiandcassi.com/family-of-twins-with-rare-and-fatal-cholesterol-disease-to-seek-fda-approval-to-deliver-cyclodextrin-into-the-brain/feed/</wfw:commentRss>
		<slash:comments>1</slash:comments>
		</item>
		<item>
		<title>How Cyclodextrin Solution Is Made For Addi and Cassi&#8217;s Intravenous Cyclodextrin Therapy</title>
		<link>http://addiandcassi.com/instructions-on-how-cyclodextrin-solution-is-made-for-addi-and-cassis-intravenous-cyclodextrin-therapy/</link>
		<comments>http://addiandcassi.com/instructions-on-how-cyclodextrin-solution-is-made-for-addi-and-cassis-intravenous-cyclodextrin-therapy/#comments</comments>
		<pubDate>Thu, 26 Nov 2009 02:47:46 +0000</pubDate>
		<dc:creator>Chris Hempel</dc:creator>
				<category><![CDATA[Cyclodextrin]]></category>
		<category><![CDATA[cholesterol drug]]></category>
		<category><![CDATA[CTD Florida]]></category>
		<category><![CDATA[Cyclodextrin Intravenous]]></category>
		<category><![CDATA[Cyclodextrin IV solution instructions]]></category>
		<category><![CDATA[endotoxin controlled]]></category>
		<category><![CDATA[FDA]]></category>
		<category><![CDATA[intrathecal cyclodextrin]]></category>
		<category><![CDATA[Niemann Pick Type C]]></category>
		<category><![CDATA[propylene glycol]]></category>
		<category><![CDATA[Renown hospital Reno]]></category>
		<category><![CDATA[subcutaneous cyclodextrin]]></category>

		<guid isPermaLink="false">http://addiandcassi.com/?p=2335</guid>
		<description><![CDATA[A number of people from around the world who have children diagnosed with the fatal cholesterol disease called Niemann Pick Type C  have asked me how our we prepare our cyclodextrin solution for Addi and Cassi&#8217;s bi-weekly IV infusions of the compound. All hydroxy propel beta cyclodextrin (HPBCD) is not the same. It&#8217;s very important [...]]]></description>
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		<slash:comments>1</slash:comments>
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