Wednesday, April 26, 2017

Nobel Prize Winning Cholesterol Researchers Brown and Goldstein Enter Cyclodextrin Field Of Study

November 10, 2009 by  
Filed under Featured Stories

I wonder how many smart cholesterol researchers have Google Alerts set up on Brown and Goldstein Labs?  If they do they might want to read this post about the Nobel Prize winning labs release of a very important cholesterol paper involving cyclodextrin and its modulation of cellular cholesterol metabolism. With their amazing new research work, [...]

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FDA Investigational New Drug Application Documents for Cyclodextrin Treatment for Niemann Pick Type C Disease

September 13, 2009 by  
Filed under FDA Cyclodextrin Filings

Here you will find detailed documents outlining Addi and Cassi’s cyclodextrin infusion treatments. We filed a compassionate use IND application to the US FDA in early 2009 to give intravenous cyclodextrin treatment which was approved.  In September 2010, FDA approved a new request to put HPBCD directly into the brains of the twins.  Addi and [...]

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Journal Of Virology Reports On Link Between HIV and Niemann Pick Cholesterol Gene: Intact Intracellular Cholesterol Trafficking Pathways Mediated by NPC1 are Needed for Efficient HIV-1 Production

June 5, 2009 by  
Filed under News

Journal of Virology May 27, 2009 Deficiency of Niemann-Pick type C-1 Protein Impairs HIV-1 Release and Results in Gag Accumulation in Late Endosomal/Lysosomal Compartments Tang Y, Leao IC, Coleman EM, Broughton RS, Hildreth JE. Human immunodeficiency virus type 1 (HIV-1) relies on cholesterol-laden lipid raft membrane microdomains for entry into and egress out of susceptible [...]

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Thank You Blue Cross Insurance!

November 11, 2007 by  
Filed under Insurance

Today is our first post in our blog and it’s a very significant day in our lives. We want to thank Anthem Blue Cross Insurance Company from the bottom of our hearts for giving Addi and Cassi a chance at life. Blue Cross has approved Zavesca for both girls and we plan to start the [...]

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