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	<title>The Addi and Cassi Fund - Niemann Pick Type C &#187; NPC News</title>
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	<description>Treatments &#38; Cures for Niemann Pick Type C - Childhood Alzheimer&#039;s</description>
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		<title>NIH Announces Therapeutic Trial With Supplement N-Acetyl Cysteine (NAC) To Treat Fatal Children&#8217;s Cholesterol Disease</title>
		<link>http://addiandcassi.com/nih-announces-therapeutic-trial-with-supplement-n-acetyl-cysteine-nac-to-treat-fatal-childrens-cholesterol-disease/</link>
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		<pubDate>Tue, 14 Jul 2009 02:08:57 +0000</pubDate>
		<dc:creator>Chris Hempel</dc:creator>
				<category><![CDATA[NPC News]]></category>
		<category><![CDATA[Research]]></category>
		<category><![CDATA[Alzheimers]]></category>
		<category><![CDATA[Biomarker Validation NPC]]></category>
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		<category><![CDATA[FDA]]></category>
		<category><![CDATA[glutathione synthesis]]></category>
		<category><![CDATA[lipid storage disorders]]></category>
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		<category><![CDATA[N-Acetyl Cysteine]]></category>
		<category><![CDATA[NAC]]></category>
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		<category><![CDATA[NICHD]]></category>
		<category><![CDATA[Niemann Pick Type C]]></category>
		<category><![CDATA[NIH]]></category>
		<category><![CDATA[Obsessive Compulsive Disorder]]></category>
		<category><![CDATA[Parkinson's]]></category>
		<category><![CDATA[trichotillomania]]></category>
		<category><![CDATA[Zavesca]]></category>

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		<description><![CDATA[You&#8217;ve got to LOVE supplements especially one called N-Acetyl Cysteine (NAC) when it can possibly help treat children afflicted with a rare and fatal cholesterol disease called Niemann Pick Type C (NPC). Considering there has only been only one clinical trial for Niemann Pick Type C ever conducted at the NIH (for a drug called [...]]]></description>
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		<title>Sphingosine and Calcium Defect Causes Niemann Pick Type C, Cholesterol Downstream Effect Of The Disease</title>
		<link>http://addiandcassi.com/a-new-intervention-strategy-for-niemann-pick-type-c/</link>
		<comments>http://addiandcassi.com/a-new-intervention-strategy-for-niemann-pick-type-c/#comments</comments>
		<pubDate>Wed, 29 Oct 2008 05:02:53 +0000</pubDate>
		<dc:creator>Chris Hempel</dc:creator>
				<category><![CDATA[NPC News]]></category>
		<category><![CDATA[Cholesterol]]></category>
		<category><![CDATA[Curcumin]]></category>
		<category><![CDATA[cytosolic free calcium]]></category>
		<category><![CDATA[glycosphingolipid]]></category>
		<category><![CDATA[lysosomal calcium]]></category>
		<category><![CDATA[Nature Medicine]]></category>
		<category><![CDATA[Niemann Pick Type C]]></category>
		<category><![CDATA[Oxford]]></category>
		<category><![CDATA[sphingosine storage disease]]></category>
		<category><![CDATA[The Platt Lab]]></category>

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		<description><![CDATA[In a recent issue of Nature Medicine, Oxford University reports that Niemann Pick Type C disease is a sphingosine storage disease that causes deregulation of lysosomal calcium.&#160; According to Oxford researchers, there is a block in the late endosome to lysosome transport in NPC disease, resulting in the downstream storage of cholesterol and glycosphingolipids (a [...]]]></description>
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