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	<title>The Addi and Cassi Fund - Niemann Pick Type C &#187; Cyclodextrin</title>
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	<description>Treatments &#38; Cures for Niemann Pick Type C - Childhood Alzheimer&#039;s</description>
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		<title>FDA Approves Request For New Cyclodextrin Treatment For Niemann Pick Type C</title>
		<link>http://addiandcassi.com/fda-approves-request-cyclodextrin-treatment-niemann-pick-type/</link>
		<comments>http://addiandcassi.com/fda-approves-request-cyclodextrin-treatment-niemann-pick-type/#comments</comments>
		<pubDate>Sun, 26 Sep 2010 00:09:27 +0000</pubDate>
		<dc:creator>Chris Hempel</dc:creator>
				<category><![CDATA[Cyclodextrin]]></category>
		<category><![CDATA[Featured Content]]></category>
		<category><![CDATA[Alzheimer’s disease]]></category>
		<category><![CDATA[childhood Alzheimer’s]]></category>
		<category><![CDATA[Children’s Hospital & Research Center Oakland]]></category>
		<category><![CDATA[cholesterol gene]]></category>
		<category><![CDATA[chris hempel]]></category>
		<category><![CDATA[cyclic oligosaccharide]]></category>
		<category><![CDATA[David Begley]]></category>
		<category><![CDATA[Dr. Caroline Hastings]]></category>
		<category><![CDATA[FDA]]></category>
		<category><![CDATA[Febreze® Fabric Refresher]]></category>
		<category><![CDATA[Hempel Family]]></category>
		<category><![CDATA[HIV]]></category>
		<category><![CDATA[HPßCD]]></category>
		<category><![CDATA[Hydroxypropyl Beta Cyclodextrin]]></category>
		<category><![CDATA[Investigational New Drug]]></category>
		<category><![CDATA[Kings College London]]></category>
		<category><![CDATA[Niemann Pick Type C]]></category>
		<category><![CDATA[NPC1]]></category>
		<category><![CDATA[Renown Regional Medical Center]]></category>
		<category><![CDATA[Trappsol® Cyclo™]]></category>

		<guid isPermaLink="false">http://addiandcassi.com/?p=3131</guid>
		<description><![CDATA[FDA Approval Received! Children’s Hospital Oakland Receives FDA Clearance to Begin World’s First Cyclodextrin Administration Into the Brains of Twins with Rare and Deadly Cholesterol Disease Sugar Molecule Used In Common Food and Household Products Like Febreze® Fabric Refresher Called Hydroxypropyl Beta Cyclodextrin (HPßCD) Will be Delivered into Twins’ Central Nervous System in an Attempt [...]]]></description>
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		<slash:comments>13</slash:comments>
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		<title>Cyclodextrins &#8211; Recipes To Make Edible Nanostructures and CD MOFs To LifeSaving Drug Treatments</title>
		<link>http://addiandcassi.com/cyclodextrins-recipes-edible-nanostructures-cd-mofs-lifesaving-drug-treatments/</link>
		<comments>http://addiandcassi.com/cyclodextrins-recipes-edible-nanostructures-cd-mofs-lifesaving-drug-treatments/#comments</comments>
		<pubDate>Tue, 07 Sep 2010 01:11:20 +0000</pubDate>
		<dc:creator>Chris Hempel</dc:creator>
				<category><![CDATA[Cyclodextrin]]></category>
		<category><![CDATA[7 ketocholesterol]]></category>
		<category><![CDATA[Angewandte Chemie]]></category>
		<category><![CDATA[blood brain barrier]]></category>
		<category><![CDATA[CD MOF]]></category>
		<category><![CDATA[Cholesterol]]></category>
		<category><![CDATA[cyclodextrin MOF]]></category>
		<category><![CDATA[edible nanostructures]]></category>
		<category><![CDATA[gamma cycloextrin]]></category>
		<category><![CDATA[gelastic cataplexy]]></category>
		<category><![CDATA[HPBCD]]></category>
		<category><![CDATA[Hydroxy Propel Beta Cyclodextrin]]></category>
		<category><![CDATA[J. Fraser Stoddart]]></category>
		<category><![CDATA[Jeremiah Gassensmith]]></category>
		<category><![CDATA[Kenneth Chang]]></category>
		<category><![CDATA[metal-organic frameworks]]></category>
		<category><![CDATA[nanoparticles]]></category>
		<category><![CDATA[New York Times]]></category>
		<category><![CDATA[Niemann Pick Type C]]></category>
		<category><![CDATA[Ronald Smaldone]]></category>
		<category><![CDATA[Trappsol]]></category>
		<category><![CDATA[United States Food and Drug Administration]]></category>
		<category><![CDATA[Wylie Dufresne]]></category>

		<guid isPermaLink="false">http://addiandcassi.com/?p=3102</guid>
		<description><![CDATA[Kenneth Chang of the New York Times reports on researchers creating edible nanostructures with gamma cyclodextrin which researchers are calling edible CD MOF (metal-organic frameworks). Of course, another amazing discovery with cyclodextrin that was found by accident! Potential applications with this gamma cyclodextrin (CD MOF) could include storing hydrogen in future fuel cells in cars. [...]]]></description>
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		<slash:comments>0</slash:comments>
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		<title>IND Application Filed With FDA To Bring Cyclodextrin Into The Brain To Treat Fatal Childhood Cholesterol Disease</title>
		<link>http://addiandcassi.com/ind-filings-intratehcal-cyclodextrin-treatment-fda/</link>
		<comments>http://addiandcassi.com/ind-filings-intratehcal-cyclodextrin-treatment-fda/#comments</comments>
		<pubDate>Sat, 17 Jul 2010 17:03:08 +0000</pubDate>
		<dc:creator>Chris Hempel</dc:creator>
				<category><![CDATA[Cyclodextrin]]></category>
		<category><![CDATA[Childhood Alzheimers]]></category>
		<category><![CDATA[Children's Hospital & Research Center Oakland]]></category>
		<category><![CDATA[CYCLO]]></category>
		<category><![CDATA[dementia treatment]]></category>
		<category><![CDATA[Dr. John Dietschy]]></category>
		<category><![CDATA[FDA]]></category>
		<category><![CDATA[Hydroxy Propel Beta Cyclodextrin]]></category>
		<category><![CDATA[intrathecal cyclodextrin]]></category>
		<category><![CDATA[Investigational New Drug Application]]></category>
		<category><![CDATA[New Cholesterol Drug]]></category>
		<category><![CDATA[Niemann Pick Type C]]></category>
		<category><![CDATA[NINDS]]></category>
		<category><![CDATA[rare disease]]></category>
		<category><![CDATA[UT Southwestern]]></category>

		<guid isPermaLink="false">http://addiandcassi.com/?p=2873</guid>
		<description><![CDATA[After months and months of work and input by doctors and researchers, Dr. Caroline Hastings at Children&#8217;s Hospital Research Center Oakland filed our second Investigational New Drug application (IND) with the FDA on July 14, 2010. The 200+ page IND filing details our request to deliver hydroxy-propel-beta-cyclodextrin (HPBCD or CYCLO) directly into Addi and Cassi&#8217;s [...]]]></description>
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		<slash:comments>4</slash:comments>
		</item>
		<item>
		<title>The Road to Building a New Orphan Drug &#8211; Am I Mad?</title>
		<link>http://addiandcassi.com/the-road-to-building-a-new-orphan-drug-am-i-mad/</link>
		<comments>http://addiandcassi.com/the-road-to-building-a-new-orphan-drug-am-i-mad/#comments</comments>
		<pubDate>Fri, 05 Feb 2010 04:41:15 +0000</pubDate>
		<dc:creator>Chris Hempel</dc:creator>
				<category><![CDATA[Cyclodextrin]]></category>
		<category><![CDATA[Addi and Cassi Hempel]]></category>
		<category><![CDATA[Center for Rare Disease Therapies]]></category>
		<category><![CDATA[Children's Hospital Oakland Research Institute]]></category>
		<category><![CDATA[cholesterol drug]]></category>
		<category><![CDATA[FDA]]></category>
		<category><![CDATA[FDA Build an Orphan Drug Workshop]]></category>
		<category><![CDATA[Filing Orphan Drug Application]]></category>
		<category><![CDATA[Hydroxy Propel Beta Cyclodextrin]]></category>
		<category><![CDATA[identical twins]]></category>
		<category><![CDATA[Keck Graduate Institute]]></category>
		<category><![CDATA[Niemann Pick Type C]]></category>
		<category><![CDATA[rare disease]]></category>
		<category><![CDATA[sugar molecule]]></category>
		<category><![CDATA[World Rare Disease Day 2010]]></category>

		<guid isPermaLink="false">http://addiandcassi.com/wordpress/?p=2518</guid>
		<description><![CDATA[On February 25-26, 2010, I will be attending the inaugural FDA Build-an-Orphan-Drug-Workshop hosted by the Center for Rare Disease Therapies at Keck Graduate Institute (KGI) in Claremont, Calif.  FDA agency experts will be on hand to provide guidance on applying for orphan drug designation. I will be attending the workshop with Dr. Ron Browne, hired [...]]]></description>
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		<slash:comments>4</slash:comments>
		</item>
		<item>
		<title>Family of Twins with Rare and Fatal Cholesterol Disease To Seek FDA Approval To Deliver Cyclodextrin Into the Brain</title>
		<link>http://addiandcassi.com/family-of-twins-with-rare-and-fatal-cholesterol-disease-to-seek-fda-approval-to-deliver-cyclodextrin-into-the-brain/</link>
		<comments>http://addiandcassi.com/family-of-twins-with-rare-and-fatal-cholesterol-disease-to-seek-fda-approval-to-deliver-cyclodextrin-into-the-brain/#comments</comments>
		<pubDate>Fri, 15 Jan 2010 21:11:37 +0000</pubDate>
		<dc:creator>Chris Hempel</dc:creator>
				<category><![CDATA[Cyclodextrin]]></category>
		<category><![CDATA[Cyclodextrin News]]></category>
		<category><![CDATA[Begley Kings College London]]></category>
		<category><![CDATA[Children's Hospital Oakland]]></category>
		<category><![CDATA[Cholesterol]]></category>
		<category><![CDATA[Compassionate Use IND Cyclodextrin]]></category>
		<category><![CDATA[Extraordinary Measures]]></category>
		<category><![CDATA[FDA]]></category>
		<category><![CDATA[identical twins]]></category>
		<category><![CDATA[intrathecal cyclodextrin]]></category>
		<category><![CDATA[intraventricular drug delivery]]></category>
		<category><![CDATA[John Crowley]]></category>
		<category><![CDATA[Lysosomal Disease Network World Conference 2010]]></category>
		<category><![CDATA[Niemann Pick Type C]]></category>
		<category><![CDATA[pharmacokinetics  cyclodextrin]]></category>
		<category><![CDATA[rare disease]]></category>
		<category><![CDATA[xanthomas]]></category>

		<guid isPermaLink="false">http://addiandcassi.com/?p=2422</guid>
		<description><![CDATA[The tagline of the new movie, Extraordinary Measures, about John Crowley’s fight to save his children from the rare and fatal Pompe disease is&#8230;.Don’t Hope For a Miracle – Make One! We are now working on making our own miracle  &#8211; a new compassionate use investigational new drug (IND) protocol and application that we plan [...]]]></description>
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		<slash:comments>1</slash:comments>
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